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Wednesday, June 27, 2012
台日經濟協議 今年可望簽定 !!
學產連接斷層 !!!! 博士後人才 只能待學界 ?
景岳/ 光惠 還是合併 !!
魚油新藥?
百達投顧 林秋瑾...生技購併題材浮現 !!
Brain insulin resistance & Type III diabetes
台灣醫生薪水人民幣20萬元 (全台資上海禾新醫院 ) !!!
Taiwan Biotech/Pharma needs multidisciplinary coordination !!!
心臟不好不能喝咖啡?? 喝咖啡可能的保護 !!!!!
皇將 董事、監察人名單
2012/6/27 鉅亨網提供 回應(0)列印轉寄討論推薦▼ 第三十四條 第6款1.發生變動日期:101/06/272.舊任者姓名及簡歷:董 事:楊 勝 輝,皇將科技股份有限公司總經理董 事:楊 世 豪,皇將科技股份有限公司副總經理董 事:施郭鳳珠,台灣慧士投資事業股份有限公司董事獨立董事:羅 文 森,佰研生化科技股份有限公司顧問獨立董事:謝 玉 田,李洲科技股份有限公司獨立董事監 察 人:張 文 添,李洲科技股份有限公司獨立董事監 察 人:林 宜 貞,東和國際旅行社專職領隊監 察 人:宋 金 玉,宋金玉代書事務所負責人3.新任者姓名及簡歷:董 事:楊 勝 輝,皇將科技股份有限公司總經理董 事:楊 世 豪,皇將科技股份有限公司副總經理董 事:施郭鳳珠,台灣慧士投資事業股份有限公司董事獨立董事:羅 文 森,佰研生化科技股份有限公司顧問獨立董事:謝 玉 田,李洲科技股份有限公司獨立董事監 察 人:張 文 添,李洲科技股份有限公司獨立董事監 察 人:林 宜 貞,東和國際旅行社專職領隊監 察 人:宋 金 玉,宋金玉代書事務所負責人4.異動情形(請輸入「辭職」、「解任」、「任期屆滿」或「新任」):任期屆滿5.異動原因:全面改選6.新任董事選任時持股數:董 事:楊 勝 輝,4,207,500股董 事:楊 世 豪,2,365,000股董 事:施郭鳳珠, 968,000股獨立董事:羅 文 森, -股獨立董事:謝 玉 田, 1,100股監 察 人:張 文 添, -股監 察 人:林 宜 貞, 176,010股監 察 人:宋 金 玉, 118,800股7.原任期(例xx/xx/xx至xx/xx/xx):98/05/08~101/05/078.新任生效日期:101/06/279.同任期董事變動比率:不適用10.其他應敘明事項:無
適量的喝咖啡 是好的 !?
Women with PCOS and sleep apnea more likely to develop prediabetes
Published on June 27, 2012 Women with polycystic ovary syndrome (PCOS) who also have obstructive sleep apnea have at least three times the risk of having prediabetes compared with women who do not have PCOS, according to a new study. The results will be presented Tuesday at The Endocrine Society's 94th Annual Meeting in Houston. "In the last few years, sleep apnea has been found to be a frequent comorbidity [coexisting condition] with PCOS, and our study shows that women who have both conditions are at greatest risk of metabolic disturbances such as prediabetes," said the study's senior author, David Ehrmann, MD, a University of Chicago professor of medicine and director of the University of Chicago Center for PCOS. "Patients who have one or both of these conditions should be screened early for Type 2 diabetes and should be monitored regularly," Ehrmann said. He and his colleagues studied 171 obese women: 121 with PCOS, a common female hormonal disorder that affects 5 to 10 percent of women of childbearing age, and 50 without PCOS. All study subjects had an oral glucose tolerance test, which measures the blood sugar level before and for two hours after the patient drinks a sugary solution. If the blood glucose level at two hours is less than 140 mg/dL, it is considered normal. Levels above 200 mg/dL indicate Type 2 diabetes, and levels between 140 and 200 mg/dL are diagnostic of impaired glucose tolerance, also called prediabetes. Prediabetes often progresses to Type 2 diabetes.
Kids eat healthier when school-based nutrition programs involve teachers, staff, parents
Exercise is key in the fight against Alzheimer's disease
June 27, 2012 by Danielle Gutierrez in Alzheimer's disease & dementia In a recent Journal of Biological Chemistry "Paper of the Week," research led by Ayae Kinoshita at the Kyoto University Graduate School of Medicine in Japan reveals the benefits of exercise in combating Alzheimer's disease. The most common cause of dementia, Alzheimer's disease results in the loss of cognitive faculty. In the majority of cases, Alzheimer's disease occurs after age 65, and factors such as diet and exercise appear to play a role in its development, with high-fat diets as a risk factor. Kinoshita's research compared the effects of 1) diet control, 2) voluntary exercise and 3) diet control plus exercise in an Alzheimer's disease mouse model. The results showed that exercise was more beneficial than diet control in reducing β-amyloid formation (a defining characteristic of Alzheimer's disease) and restoring memory loss induced by a high-fat diet in these mice. Moreover, Kinoshita's team found that the effect of diet control plus exercise was not significantly different than exercise alone. They attribute the positive effects of exercise to increased degradation of β-amyloid deposits in the brain. "Based on the results in this research," Kinoshita suggests, "exercise should be given priority to prevent Alzheimer's disease." From the article: "Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice" by Masato Maesako, Kengo Uemura, Masakazu Kubota, Akira Kuzuya, Kazuki Sasaki, Naoko Hayashida, Megumi Asada-Utsugi, Kiwamu Watanabe, Maiko Uemura, Takeshi Kihara, Ryosuke Takahashi, Shun Shimohama and Ayae Kinoshita Read the Paper in Press version here: http://www.jbc.org … 358.abstract Journal reference: Journal of Biological Chemistry
ESCs and iPSCs demonstrate similar survival and neural differentiation capabilities
Published on June 27, 2012 Researchers in Japan who evaluated the risks and efficacy of transplanting two varieties of stem cells into mouse cochlea have concluded that both adult-derived induced pluripotent stem (iPS) cells and mouse embryonic stem (ES) cells demonstrate similar survival and neural differentiation capabilities. However, there is a risk of tumor growth associated with transplanting iPS cells into mouse cochleae. Given the potential for tumorigenesis, they concluded that the source of iPS cells is a critical issue for iPS cell-based therapy. Their study is published in a recent issue of Cell Transplantation (21:4), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/, "Hearing loss affects millions of people worldwide," said Dr. Takayuki Nakagawa of the Department of Otolaryngology, Graduate School of Medicine, Kyoto University, Japan. "Recent studies have indicated the potential of stem-cell based approaches for the regeneration of hair cells and associated auditory primary neurons. These structures are essential for hearing and defects result in profound hearing loss and deafness." The authors noted that embryonic stem cells have previously been identified as promising candidates for transplantation, however they have also been associated with immune rejection and ethics issues. Consequently, this study compared the survival and neural differentiation capabilities of ES and three clones of mouse iPS cells. "Our study examined using induced pluripotent stem cells generated from the patient source to determine if they offer a promising alternative to ES cells," explained Dr. Nakagawa. "In addition, the potential for tumor risk from iPS cells needed clarification." Four weeks after transplantation, the researchers found that the majority of cochleae that had been transplanted exhibited the settlement of iPS or ES-derived neurons. However, there was a difference in the number of cells present based on cell lines. They noted that the number of cells able to be transplanted into cochleae is limited because of the cochleae's tiny size. Thus, the number of settled cells is low.
旭富 愛滋病藥中間體 出貨增至10公噸!!!
旭富 今年獲利拚新高 【經濟日報╱記者黃文奇/台北報導】 2012.06.28 02:34 am 上海原料藥展今(28)日閉幕,原料藥廠旭富(4119)參展傳出佳績;旭富昨日表示,此次展出已完成約40次採購洽談,可望推升下半年訂單能見度。法人估,今年旭富獲利可望大躍進,改寫歷史新高。 旭富今年首季稅後純益約5,600萬元,每股稅後純益為1.16元,昨日股價收54.5元,上漲0.3元。 旭富表示,此次原料藥展每天都安排至少8到10個採購洽談會議,主要針對長期合作,進行意見交流。據了解,旭富大客戶羅氏、亞培等,今年都繼續追加訂單,譬如亞培愛滋病用藥,將向旭富繼續追加中間體訂單;因此今年高單價愛滋病藥物中間體,出貨量可望翻倍,約從去年的5公噸增至10公噸,提升營收占比約5%。 法人表示,1到5月來看,旭富稅前盈餘年增率達到16.8%,下半年動能稍緩,但仍不會呈現衰退,全年出貨量可望達2,300公噸。 分析師說,今年1到5月旭富毛利率約達30%以上,從1到5月稅前自結數來看約1.03億元,推估上半年稅後純益可能進1億元,若下半年動能持平,全年稅後純益可望上攻1.8到2億元,將刷新歷史紀錄。在投資計畫方面,旭富說,今年桃園縣蘆竹廠由於部分產能趨近滿載,目前12條產線將再加擴1條,投資金額約8,000萬元,年底前可望投產。 【2012/06/28 經濟日報】
Simple blood test may help physicians track progression of RA disease activity
Published on June 27, 2012 A simple blood test may help physicians track the progression of rheumatoid arthritis disease activity, say researchers at the University of Alabama at Birmingham. In a paper published online on June 26, 2012, in Arthritis Care and Research, the UAB-led international research team says that a blood test measuring 12 biomarkers for RA is a valid and potentially useful tool in managing the disease. "Previously, the disease activity of RA was assessed through clinical observation by a physician, noting the number of tender and swollen joints and assessing pain and functional abilities," said Jeffrey Curtis, M.D., associate professor in the division of clinical immunology and rheumatology and lead author of the study. "This blood test measures the underlying amount of RA activity within the joints using sophisticated biochemical means intended to reflect the underlying pathophysiology of the disease. A highly reproducible, easily standardized blood test that measures multiple biologic pathways to augment a physician's and patient's clinical assessment has not been previously available to physicians." Curtis says the test emphasizes the activity of underlying biological pathways rather than external signs and symptoms and should therefore provide information that is different from, and complementary to, clinical assessment. He suggests the test may also help assess treatment response in patients. The test could show in just a few weeks whether a particular therapy is effective, rather than within three to four months as in current practice.
Menopausal women could "work out" their hot flashes
June 27, 2012 in Health (Medical Xpress) -- Menopausal women who exercise may experience fewer hot flashes in the 24 hours following physical activity, according to health researchers. In general, women who are relatively inactive or are overweight or obese tend to have a risk of increased symptoms of perceived hot flashes, noted Steriani Elavsky, assistant professor of kinesiology at Penn State. Perceived hot flashes do not always correspond to actual hot flashes. Most previous research analyzed only self-reported hot flashes. This is the first study known to the researchers to look at objective versus subjective hot flashes. Elavsky and colleagues studied 92 menopausal women for 15 days. The women recruited for this study were different from many earlier menopause studies, said Elavsky. In the past, women in menopause studies were experiencing severe symptoms and seeking help. They were probably not representative of the general population. "Our sample included women with mild to moderate symptoms and they were recruited for a study of physical activity, not for a study of menopause," said Elavsky. "We recruited women residing in the community. We used recruitmentsources that included a variety of outlets in the community frequented by women, like libraries, fairs, gyms, advertisements in local newspapers, etc." The women were 40 to 59 years old, with an average of two children and were not on hormone therapy. During analysis the researchers separated the women into normal weight and overweight/obese categories and higher fit and lower fit categories. These categories were not necessarily mutually exclusive. The participants wore accelerometers to monitor their physical activity and also wore monitors that measured skin conductance, which varies with the moisture level of the skin. Each participant recorded the individual hot flashes she had throughout the 15-day period on a personal digital assistant. African healthcare - Think you know Africa? Take another look. - www.novartis.com Through these two methods of recording hot flashes, the researchers found the frequency of objective and subjective hot flashes. Objective hot flashes occurred when the monitor recorded them; subjective hot flashes occurred when the woman reported them. When an objective and a subjective hot flash were recorded within five minutes of each other, it was considered a "true positive" hot flash, the researchers report in the current issue of Menopause. "Some physiological explanations would suggest that performing physical activity could increase hot flashes because it acutely increases body core temperature," said Elavsky. To the contrary, the researchers found that this premise was not true, as on average the women in the study experienced fewer hot flash symptoms after exercising. However, the women who were classified as overweight, having a lower level of fitness or were experiencing more frequent or more intense hot flashes, noticed the smallest reduction in symptoms. It is not yet known if a woman could use diet and exercise to lose weight and become more fit and therefore experience fewer hot flashes, but it is a possibility worthy of future investigation, noted the researchers. "For women with mild to moderate hot flashes, there is no reason to avoid physical activity for the fear of making symptoms worse," said Elavsky. "In fact, physical activity may be helpful, and is certainly the best way to maximize health as women age. Becoming and staying active on a regular basis as part of your lifestyle is the best way to ensure healthy aging and well being, regardless of whether you experience hot flashes or not." Also working on this research were Joaquin U. Gonzales, assistant professor of exercise physiology, Texas Tech University; David N. Proctor and Nancy I. Williams, both professors of kinesiology and physiology, Penn State; and Victor W. Henderson, professor of health research and policy and neurology and neurological sciences, Stanford University. The National Institute of Child Health and Human Development supported this research. Provided by Pennsylvania State University
塑化劑 (di-ethylhexyl phthalate, DEHP) 與 幼兒肥胖 高度相關 !!
【公告停止適用「塑化劑污染食品之處理原則」之Q&A】(100.08.01更新)
Q1:此公告之執行是否達預期效益?Q2:為何選擇8月1日公告停止適用?有什麼指標?
Q3:公告停止適用後,政府如何保證食品之安全?Q4:對於那些已經食用含塑化劑產品的民眾,政府是否有提供他們醫療上的協助?
Q1:此公告之執行是否達預期效益?A:
(一) 本次食品添加物起雲劑含DEHP之食品污染事件,係屬黑心廠商惡意將不得添加於食品中之成分添加於食品中之犯罪行為。
(二) 原公告之用意為希望透過政府、企業及民間的共同努力,迅速平息事件,恢復市場次序。
(三) 目前犯罪嫌疑人已羈押,且政府經過2個月努力,涉案廠商及產品已無新增,未發現有惡意污染產品,已無系統性污染。
Q2:為何選擇8月1日公告停止適用?有什麼指標?A:經評估下列因素,行政院決定停止公告的適用。
(一) 全面掌控:自6月14日起,即無增加涉案廠商及涉案產品。
(二) 輿情平緩:消費者專線、長官信箱、輿情報導、健康諮詢人數、消保申訴案件、記者詢問皆大幅下降、漸趨平緩。
(三) 產品淨化:市售抽驗產品完成檢驗,未發現有惡意系統性污染產品。
(四) 全數銷毀:除檢察機關查扣證物暫緩銷毀外,其餘受污染產品全數於7月29日前銷毀。
Q3:公告停止適用後,政府如何保證食品之安全?A:為了確保民眾飲食之安全,政府將有已下作為:
(一) 源頭管理:衛生署與環保署針對列管塑化劑毒化物強化運作管理,建立兩署間業務通報機制,強化勾稽及異常警示功能機制,防杜不法。
(二) 強制登錄:強制落實食品添加物產業登錄制度,並將食品中塑化劑之含量列為市場監測之例行稽查抽驗項目。
(三) 風險偵測:進行國產及進口食品塑化劑含量之調查與追蹤系統,建立國人攝取暴露量之風險評估,瞭解食品中塑化劑背景值外,偵測異常,防止其他可能污染源。
(四) 容器管理:蒐集資料,修正塑膠類食品包裝及食品容器之規格、衛生標準及使用規範,期以降低食品中塑化劑之含量。
(五) 製程改善:研擬工業準則,透過製造過程或器具之改善,降低食品中塑化劑之含量。
(六) 稽查取締:實施全面性食品稽查計畫,監測任何可能污染源,並加強衛生、檢調及各相關單位之合作及取締工作,嚴懲不法之業者。
Q4:對於那些已經食用含塑化劑產品的民眾,政府是否有提供他們醫療上的協助?A:政府已提供民眾對健康疑慮的諮詢管道,並已建立後續評估追蹤的機制:
(一) 持續關懷:衛生署已研擬申訴者主動醫療輔導及追蹤評估標準作業流程,對申訴人進行關懷。
(二) 後續追蹤:國家衛生研究院將成立”國家環境毒物研究中心”,持續針對塑化劑追蹤並研究塑化劑對國人健康影響之流行病學研究。
【食品藥物管理局Q&A】(100.07.29更新)
Q3. 什麼是「環境荷爾蒙」? Q4. 為什麼我們會吃到塑化劑? 體內會有塑化劑?Q5. 經由飲食進入人體的塑化劑會排出體外嗎? 多久才會排出?Q6. 是不是吃過受DEHP污染的食品或飲料,就會影響身體健康?Q7. 曾食用或飲用受塑化劑DEHP污染的食物,對人體影響為何? 會不會影響生殖功能?Q8. 曾食用或飲用受塑化劑DEHP污染的食物,會不會引起癌症?Q9. 食用或飲用多少受塑化劑DEHP污染的食物才有危險性? Q10. 懷孕的我需不需要去接受特別產檢呢?Q11. 小孩吃了含有塑化劑的食品怎麼辦? 我需不需要特別帶小孩去接受血液、尿液檢驗?
Q1. 什麼是「塑化劑」? 1.塑化劑並不是合法的食品添加物。
2.塑化劑或稱增塑劑、可塑劑,是一種增加材料的柔軟性或是材料液化的添加劑。其添加對像包含了塑膠、混凝土、牆版泥灰、水泥與石膏等等。
3.塑化劑種類多達百餘種,但使用的最普遍的即是一群稱為鄰苯二甲酸酯類的化合物;例如DBP、DEHP、DINP、DIDP、BBP及DNOP等。
Q2. 常見的塑化劑之毒性為何?
世界衛生組織(WHO)-癌症研究中心(IARC),2011年五月最新資料;
歐盟2008年DEHP等塑化劑之風險評估報告;
歐洲食品安全局;
美國環保署危害物整合性風險資料庫;
*日本東京都立研究所「內分泌干擾物質(67種)彙編」
名稱
|
用途
|
致癌性
|
生殖毒性
|
*內分泌干擾物質
(環境荷爾蒙) |
DEHP
Di-(2-ethylhexyl) phthalate
鄰苯
二(2-乙基己基)酯
|
食品包裝
醫療器材
建築材料
塑化劑
|
對動物有
WHO-IARC: 2B
| 動物:有 | |
BBP
Butyl benzyl phthalate
鄰苯
丁基苯酯
|
建築材料(含PVC)
人造皮革
汽車內飾
塑化劑
|
對動物有
WHO-IARC: 3
|
動物:有
人類:研究中 |
是
|
DBP
Di-n-butyl phthalate
鄰苯
二丁酯
|
食品包裝
乳膠黏合劑
溶劑
|
無足夠科學證據證明
WHO-IARC:無
|
動物:有
人類:研究中 |
是
|
DINP
Diisononyl phthalate
鄰苯二甲酸
二異壬酯
|
鞋底
建築材料
塑化劑
|
對動物有
WHO-IARC:無
| 人類:研究中 |
不是
|
DIDP
Diisodecyl phthalate
鄰苯
二異癸酯
|
電纜線
膠鞋
地毯黏膠
橡膠襯墊
|
無足夠科學證據證明
WHO-IARC:無
| 人類:研究中 |
不是
|
DnOP
Dioctyl
phthalate
鄰苯
二辛酯
|
地板膠
聚乙烯磁磚
帆布
塑化劑
|
無足夠科學證據證明
WHO-IARC:無
| 人類:研究中 |
不是
|
DIBP
Di-isobutyl phthalate
鄰苯
二異丁酯
|
油漆
紙漿
紙板
接著劑
塑化劑
黏度調整劑 |
無足夠科學證據證明
WHO-IARC:無
| 人類:研究中 |
不是
|
DEP
Diethyl
Phthalate
鄰苯
二已酯 |
溶劑
護理用品
油墨
|
無足夠科學證據證明
WHO-IARC:無
|
動物:有
人類:研究中 |
是
|
DMP
Dimethyl phthalate
鄰苯
|
溶劑
個人衛生用品
護理用品
油墨
|
無足夠科學證據證明
WHO-IARC:無
| 人類:研究中 |
不是
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Q3. 什麼是「環境荷爾蒙」? 1.環境荷爾蒙泛指「來自環境的內分泌干擾物質」。
2.一些人工合成化學物質所造成的環境污染後,透過食物鏈再回到我們身體(或其他生物體內),它可以模擬體內的天然荷爾蒙,干擾荷爾蒙作用,進而影響身體內的最基本的生理調節機能,又環境荷爾蒙化學污染物可經由母乳傳給下一代,因此環境荷爾蒙可能會影響生物體的生殖機能與發育。
(1)在剛漆完油漆的房間或是最近才裝好地板的屋子,室內空氣比室外空氣含有更多的DEHP。
(2)當應用塑膠容器或包材(尤其是PVC類)儲存食物時,DEHP會微量溶出殘留在食物中;所以,平時國內、外對市售食品中塑化劑殘留量的調查結果,均可發現DEHP等塑化劑的蹤影,DEHP的殘留量,在每毫升茶飲料中約為2.0×10-6~4.8×10-6 毫克、每毫升植物油則約為8.35×10-4~2.387×10-3毫克,而國外針對乳製品所作之調查結果,乳酪(起士)中DEHP的殘留量約為3×10-4~5.5×10-3
毫克,這樣的結果即代表著:
A. 不管是水性的茶飲料或油性的植物油等食物,在貯存過程中,塑化劑均會微量從塑膠容器釋出。
B. 因為植物油與塑化劑皆是油性物質,故導致塑化劑的溶出量會較一般非油性食物高。
C. 此外,由於乳酪的原料是牛奶,除了含油脂外,亦經加工過程層層濃縮,所以會有較高的殘留量。
2.依據英國、美國、瑞典、加拿大、日本、韓國及我國的相關研究與調查結果,顯示透過飲食而攝入DEHP之情形普遍存在,各國可容忍之60公斤成人每日攝取量範圍為1.2~8.4毫克。
3.根據調查國人每日自食物攝入DEHP的量推估約為1.029 mg。
2.塑化劑DEHP代謝速度非常快,進入人體後於12~24小時內約有一半的DEHP及其代謝物會藉由尿液排出體外;大部份的DEHP及其代謝物會於24~48小時由尿液或糞便排出。
3.塑化劑DINP亦會被人體迅速代謝,72小時內有85%由糞便中排出,其餘部分則由尿液排出。
4.在48小時內停止飲用含有DEHP之產品,體內DEHP濃度便會快速下降,因此不必過於擔憂。
Q6. 是不是吃過受DEHP污染的食品或飲料,就會影響身體健康?
如果長期吃超過每日可容忍攝取量時,才可能會對人體造成影響,並說明如下:
1.目前各國對DEHP規範的每日可容忍攝取量(TDI)上限範圍為0.02~0.14 毫克/公斤,以60公斤成人為例,每日攝取量上限為1.2~8.4毫克;亦即每天吃進的DEHP含量在上限範圍內時,就算吃一生對身體都不會造成影響。
2.雖然長期吃超過此劑量時,對人體有可能會造成影響,但仍有許多因素決定是否會引起有害的健康效應,及影響健康效應的方式和嚴重性;這些因素包括:
(1)劑量的多寡。
(2)暴露期間的長短。
(3)暴露的途徑或過程(呼吸、食入、飲用或皮膚接觸)。
(4)混合其他化學物質的暴露。
(5)還有個人的特異性,如年齡、性別、營養狀況、家族特徵、生活型態和健康狀態等都有相關。
Q7. 曾食用或飲用受塑化劑DEHP污染的食物,對人體影響為何? 會不會影響生殖功能?1. 根據相關文獻顯示,自從DEHP開始使用40年以來,發現有許多對人體可能之影響,例如:男性陰莖短小、隱睪症、女性性早熟 (一般指小於8歲的女生)。
2. 但是以上研究皆未顯示多少血中濃度的DEHP或累計多久時間的使用會造成傷害,所以大家不用為此過度驚慌。
Q8. 曾食用或飲用受塑化劑DEHP污染的食物,會不會引起癌症?
目前尚無直接證據顯示DEHP會導致人類罹患癌症,因為:
1.依據文獻報告,到目前為止並無針對人體作DEHP的致癌風險研究,雖有動物實驗的結果,但是否可以引用到人體,值得懷疑。
2.在動物實驗方面,1980年代曾有報告指出DEHP會引起動物肝癌,另外還有研究認為會引起白血病及其他腫瘤等,但是相關研究數據數量並不多,不足以作為評估依據。
3.而在老鼠罹患肝癌的研究上,研究人員指出,對於老鼠致癌機制中所需的peroxisome,在人體身上並沒有,所以相關疾病不太會在人類身上發生。
Q9. 食用或飲用多少受塑化劑DEHP污染的食物才有危險性?
根據我國國家衛生研究院的研究評估,若依美國所做每日總攝取量(TDI)管制值每人每天每公斤20微克(μg)的標準,推估:
1.每週一瓶並不會增加風險。
2.若成人長期每天喝一瓶受污染的飲料(DEHP濃度12ppm,每一瓶350毫升),將來可能發生生殖功能異常的風險可能會增加。
3.因此,除非長期且每日飲用遭污染的飲料或果汁,導致DEHP每日之攝取量超過TDI限值,否則應該不致對人體產生健康上之傷害。
Q10. 懷孕的我需不需要去接受特別產檢呢?產檢不易看出胎兒有無生殖系統影響,可藉由新生兒出生後仔細檢查,但塑化劑DEHP在停用後會迅速排出體外,孕婦不需太過擔心,只需定期作產檢、遠離塑化劑、心情上保持愉悅即可,如有相關疑慮,可以與您的產檢醫師討論。
Q11. 小孩吃了含有塑化劑的食品怎麼辦? 我需不需要特別帶小孩去接受血液、尿液檢驗?1. 目前血液、尿液檢驗,並沒有相關文獻數據,以供判讀塑化劑對人體的影響。
2. 因此兒科醫學會並不建議進行血液尿液的例行性檢查,重要的是兒童飲食應均衡,多吃富含維他命的蔬果、白開水及湯品等有助於排泄,不用刻意長期補充保健食品。
【 PVC醫療器材相關問題】
http://www.fda.gov.tw/itemize.aspx?itemize_sn=4970&pages=0&site_content_sn=310
(點擊上列連結即可進入)
【化粧品相關問題】
http://www.fda.gov.tw/content.aspx?site_content_sn=2509&showview=1
(點擊上列連結即可進入)
【藥品相關問題】http://www.fda.gov.tw/itemize.aspx?site_content_sn=1239&itemize_sn=5009&showview=1
(點擊上列連結即可進入)
【食品中塑化劑污染衛教手冊】http://www.fda.gov.tw/files/site_content/食品中塑化劑污染衛教手冊.pdf(點擊上列連結即可下載檔案)
提供單位:國民健康局
【5少5多減塑撇步】http://www.fda.gov.tw/files/site_content/5少5多減塑撇步.pdf
(點擊上列連結即可下載檔案)
提供單位:國民健康局
【塑化劑DEHP參考資料(醫療衛生人員版)】http://www.fda.gov.tw/files/site_content/塑化劑DEHP參考資料(醫療衛生人員版).pdf(點擊上列連結即可下載檔案)
提供單位:臺北榮民總醫院臨床毒藥物諮詢中心
【相關單位提供之Q&A】
http://www.fda.gov.tw/files/site_content/Q&A1000616p1.pdf
(點擊上列連結即可下載檔案)
提供單位:行政院衛生署、臺灣兒科醫學會、台灣婦產科醫學會、
中華民國內分泌學會以及台灣家庭醫學醫學會。
Source: TFDA