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Wednesday, July 4, 2012

養身美食! 草莓奶油? 草莓就好了 ....


Strawberry extracts actively stimulate proteins that offer protection against cardiovascular disease Published on July 4, 2012 Strawberries, the traditional summer treat associated with Wimbledon could be serving up some unexpected health benefits. Scientists at the University of Warwick have been studying the beneficial effects of strawberries on our cardiovascular health, particularly around how they prevent the development of heart disease and diabetes. Professor Paul Thornalley from Warwick Medical School heads the team that discovered extracts from strawberries positively activate a protein in our bodies called 'Nrf2' which is shown to increase antioxidant and other protective activities. This protein works to decrease blood lipids and cholesterol, the very things which can lead to cardiovascular problems. Eating strawberries has previously been found to counter post-meal blood glucose and low density lipoprotein, or 'bad' cholesterol and therefore decrease risk of diabetes and heart disease, but this is the first time that strawberry extracts have been proved to actively stimulate proteins that offer us protection against disease.
Professor Thornalley explained: "We've discovered the science behind how strawberries work to increase our in-built defences to keep cells, organs and blood vessels healthy and which can reduce the risk of developing cardiovascular problems such as heart disease and diabetes. "So don't feel guilty about serving up strawberries and cream … although I'd suggest more strawberries and less or even no cream!" Screening and mathematical modelling techniques developed at the University of Warwick can now take this research further to help identify the best varieties of strawberries, how they are served or processed and how many strawberries should be eaten for optimum health benefit.
Source: http://www2.warwick.ac.uk/newsandevents/pressreleases/strawberry_wimbledon-superfruit   

Nuclear factor (erythroid-derived 2)-like 2, also known as NFE2L2 or Nrf2, is a transcription factor that in humans is encoded by the NFE2L2 gene.NFE2L2 induces the expression of various genes including those that encode for several antioxidant enzymes, and it may play a physiological role in the regulation of oxidative stress. Investigational drugs that target NFE2L2 are of interest as potential therapeutic interventions for oxidative-stress related pathologies.






Gene expression pattern of the NFE2L2 gene.



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