持續用Statins改善出血中風預後

Statins can lead to increased survival after hemorrhagic stroke, study finds 24-09-2014  Patients who were treated with a statin in hospital after suffering from a hemorrhagic stroke were significantly more likely to survive than those who were not, according to a study published in JAMA Neurology. The study included 3,481 individuals who were admitted to any of 20 Kaiser Permanente hospitals in Northern California with a hemorrhagic stroke over a 10-year period. Researchers looked at patient survival and discharge 30 days after the stroke. Patients treated with a statin while in the hospital were more likely to be alive 30 days after suffering a hemorrhagic stroke than those who were not treated with a statin — 81.6% versus 61.3%. Patients treated with a statin while in the hospital were also more likely to be discharged to home or an acute rehabilitation facility than those who were not — 51.1% compared to 35%.Patients taking a statin as an outpatient prior to experiencing a hemorrhagic stroke who did not receive a statin as an inpatient had a mortality rate of 57.8% compared with a mortality rate of 18.9% for patients using a statin before and during hospitalization.

STOPPING STATINS CAN CARRY RISKS  Lead author Alexander Flint, of the Kaiser Permanente Department of Neuroscience in Redwood City, California, said: "Previous research has suggested that treating patients with statins after they suffer hemorrhagic stroke may increase their long-term risk of continued bleeding. Yet the findings of our study suggest that stopping statin treatments for these patients may carry substantial risks." The researchers concluded that statin use is strongly associated with improved outcomes after hemorrhagic stroke, and that discontinuing statin use is strongly associated with worsened outcomes after hemorrhagic stroke. This study was conducted by the same researchers who recently discovered that the use of cholesterol-lowering statins can improve survival in victims of ischemic stroke. Ischemic stroke is caused by a constriction or obstruction of a blood vessel that blocks blood from reaching areas of the brain, while hemorrhagic stroke, also known as intracerebral hemorrhage, is bleeding in the brain.