保養品(化妝品) Top 20 過敏源!!

北美接觸性皮膚炎團體NACDG; North American Contact Dermatitis Group) ，統計女性對保養品(化妝品) 中，最易引起過敏前20名的保存劑(防腐劑) 與香味劑。

 

排名		過敏源		過敏反應 (次)		比例 (%); n = 1582 女性
1		Quaternium-15 (季銨鹽) 2%		323		20.4
2 & 3		Myroxylon pereirae (balsam of Peru 秘鲁香脂) 25%		302		19.1
2 & 3		Fragrance mix 8% **		302		19.1
4		p-Phenylenediamine (對苯二胺)1%		247		15.6
5		Methyldibromoglutaronitrile/phenoxyethanol (甲基二溴戊二/ 苯氧乙醇) 2%		131		8.3
6		Formaldehyde (甲醛) 1%		108		6.8
7		Tosylamide formaldehyde resin (甲苯磺酰胺/甲醛樹脂)10%		97		6.1
8		Cocamidopropyl betaine (甜菜鹼界面活性劑, 季銨鹽) 1%		84		5.3
9		Glyceryl thioglycolate (甘油巯基乙酸酯) 1%		83		5.3
10 & 11		Diazolidinyl urea (尿素醛) 1%		79		5
12		DMDM hydantoin (DMDM乙內酰脲) 1%		77		4.9
13		Lanolin alcohol (羊毛脂醇) 30%		71		4.5
14 & 15		Imidazolidinyl urea (咪坐丁尿素) 2%		70		4.4
14 & 15		Methylchloroisothiazolinone/methylisothiazolinone (甲基氯异噻唑啉酮/ 甲基異噻唑啉酮 100 ppm*		70		4.4
16		Methyl methacrylate (甲基丙烯酸甲酯) 2%		65		4.1
17		Amidoamine (胺基酰胺) 0.1%		63		4
18		Propylene glycol (丙烯乙二醇) 30%		61		3.9
19		Imidazolidinyl urea 2%		51		3.2

 

**Fragrance Mix I (8.0% in petrolatum)

l          Amyl cinnamic alcohol 1.0%

l          Cinnamic alcohol 1.0%

l          Eugenol 1.0%

l          Cinnamic aldehyde 1.0%

l          Hydroxycitronellal 1.0%

l          Geraniol 1.0%

l          Isoeugenol 1.0%

l          Oak moss absolute 1.0%

l          Sorbitan sesquioleate (emulsifier) 5.0%

 

Reference: Allergic contact dermatitis to preservatives and fragrances in cosmetics. Skin Therapy Lett. 2011;16(4):1-4.