New Swine-Origin Flu Cases Reported By Todd Neale, Senior Staff Writer, MedPage Today Published: December 27, 2011 Since the middle of August, the CDC has received 12 reports of human infections with a swine-origin influenza A (H3N2) virus, the agency announced. The cases come from five states -- Indiana (two), Iowa (three), Maine (two), Pennsylvania (three), and West Virginia (two), Douglas Jordan, MA, of the CDC's influenza division, and colleagues reported online in Morbidity and Mortality Weekly Report. All but one of the affected individuals were younger than 18, and half had had no contact with pigs. Three were hospitalized, and all have fully recovered. Although there is still limited information available on how efficiently the virus is transmitted between pigs, between humans, or between species, evidence indicates at least minimal human-to-human transmission of the variant, which contains genes from avian, human, and swine flu strains. The report, which follows previous MMWR dispatches on two cases in Indiana and Pennsylvania and the three in Iowa, focused on the three most recent cases -- an adult male in Indiana and two children in West Virginia. The infecting strain was similar to the previous cases. It was a swine-origin influenza A (H3N2) virus with the matrix (M) gene from the pandemic influenza A (H1N1) virus. To distinguish the virus from the circulating seasonal H3N2, health officials have dubbed it H3N2v. The man in Indiana, who had direct occupational contact with swine, was hospitalized for four days after developing fever, cough, shortness of breath, nausea, vomiting, and body aches. After preliminary testing by state health officials revealed infection with an inconclusive influenza A virus, samples were sent to the CDC, which confirmed that it was the new variant. The two children in West Virginia, both younger than 5, attended the same daycare facility. One had been hospitalized for an unrelated condition two days before developing fever. The other developed fever, cough, diarrhea, and rhinorrhea and recovered fully without receiving any medical care. Neither of the children had traveled recently nor had exposure to swine. Even though they had been in contact with each other, the CDC said it was unlikely the virus was passed directly from one to the other because illness onset in the two cases was separated by more than 10 days."This represents a scenario of limited human-to-human transmission occurring in a daycare setting," the authors wrote. "Therefore, clinicians also should consider the possibility of influenza A (H3N2)v infections in patients who have not had exposure to swine, particularly young children in those states where ... cases have been reported."All of the variant viruses tested so far have been susceptible to oseltamivir (Tamiflu) and zanamivir (Relenza), and resistant to amantadine and rimantadine. Young children likely have little preexisting immunity to the viruses, although older children and adults who have been exposed to other H3N2 viruses in the past might have limited immunity, according to the authors. The trivalent seasonal vaccine, which protects against an H3N2 strain, is not expected to provide significant protection against the variant.
Tuesday, December 27, 2011
新型豬流感病毒(H3N2v)感染人類!!
美國豬流感 首現人傳人 北京新浪網 (2011-12-28) 美國公共衛生官員日前發布西弗吉尼亞州一名兒童受到豬流感H3N2病毒感染的病例，也公布威斯康星州一個受新型H1N1豬流感感染的病例，該種病毒此前並未在人類身上出現過，是人類被這種病毒傳染的首例。報導稱，威斯康星州的病例看似孤立事件、僅此一例，沒有擴大傳播的跡象。不過，據美國疾病控制與預防中心23日發布的細節，西弗吉尼亞州的這名兒童是被人感染，而非受豬感染，而且在這名兒童住的未公布名稱的小區里，有某種程度人傳人的現象出現。
或有更多病例未報告 這起病例是美國在5個州里感染H3N2病毒的第12個病例。美國疾病控制與預防中心承認，可能還有更多病例未被美國的流感監測系統發現。美國疾病控制與預防中心流感部門的流感傳染病學小組主持人布瑞斯博士說："我們不認為這些就是全部病例。"美國以外，迄今沒有別國通報人類受到H3N2豬流感病毒感染的案例。另一份報告透露威斯康星州病例的細節，這個病例涉及一種新的H1N1病毒，有來自禽流感、豬流感與人類流感病毒的基因。美國疾病控制與預防中心的報告表示，國際流感科學伙伴已同意以新名字稱呼這些病毒。
美國加強監控H3N2 美國疾病控制與預防中心發布報告，指該中心正加強監控豬流感的H3N2亞型病毒。美國廣播公司新聞網報導，全美各州的公共衛生實驗室，倘若發現疑似感染病例，應立即通報疾病管制與預防中心。自8月12日起，全美已報告的12名H3N2亞型病毒感染者分散在印第安那、衣阿華、緬因、賓夕法尼亞和西弗吉尼亞等五州。12名患者中有11名為孩童，曾有3人住院治療，半數感染者沒有接触豬衹。王裳
豬流感病毒變種多 H3N2在2009年年初傳染時，農業部門抗議公衛官員將這新型病毒稱為豬流感病毒。豬肉銷售驟減，豬肉產業擔心，隨著豬流感傳人的新病例報告發布，類似情況可能再度發生。世界衛生組織和聯合國糧農組織已同意把這些病毒命名為"H3N2變異體"。2010年以來在豬衹間傳染的新病毒H1N1也以同樣原則叫做H1N1變異體。據稱，此一變種新型流感病毒結合了人類流感、禽流感（H5N1）及人豬共通流感（H1N1）的基因，可以在人與人之間傳播。
台灣第9例流感併發症死亡!!
國鼎生技研發長黃三保 下溫武哲 上
國鼎生技：國鼎生技科技研發部主管異動 鉅亨網新聞中心 2011-12-27 第三十四條 第11款1.人員變動別（請輸入發言人、代理發言人、財務主管、會計主管、研發主管或內部稽核主管）:研發主管 2.發生變動日期:100/12/27 3.舊任者姓名、級職及簡歷:黃三保(科技研發部總監)4.新任者姓名、級職及簡歷:溫武哲(研發部副總經理)5.異動情形（請輸入「辭職」、「職務調整」、「資遣」、「退休」、「死亡」或「新任」）:職務調整6.異動原因:因內部管理需求 7.生效日期:100/12/27 8.新任者聯絡電話:無 9.其他應敘明事項:無
Taiwan`s Biotech Ind. to Grow Explosively Over Next 2 Years
2011/12/27 Taipei, Dec. 27, 2011 (CENS)--Seven new drugs developed in Taiwan have been approved by the Food and Drug Administration (FDA) of the United States for third-stage clinical trials, and some of them may be commercialized in 2012, said Wong Chi-huey, president of Taiwan's highest-level national research body Academia Sinica, at the 2011 Safety and Quality (SNQ) Award ceremony in Taipei, who added that over the next two to three years Taiwan`s biotechnology industry will grow explosively. Taiwan`s biotechnology line is globally recognized, and besides the said seven new drugs in third-stage trials, as many as 60 Taiwan-developed drugs now are in first- or second-stage trials, said Wong. In 2012, Wong stressed, several new drugs will be commercialized to mark a new milestone for Taiwan`s biotech industry as well as show the island`s strength to the whole world. According to Wong, biotech is an industry relevant to health, beauty and innovation, so players in the field have to be devoted for a long period to bear fruit. In the past 20 to 30 years or so, he added, the biotech industry in Taiwan has faced many challenges, including even misunderstanding due to politicking, but all adverse factors will be overcome.
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