Wednesday, May 5, 2010

Hopeful radiation therapy for patients: An alternative way of internal radiation


Conventional approaches for certain cancer patients treatment are using drugs or specialized medical instrument with therapeutical means (radiation, heat, ect.) Recently, a targeting molecule (drug) conjugated with a radionuclide offers a personalized treatment for a internal radiation therapy.The most updated status is on phase III in U.S.. An eye-catching news is not merely from scientific and clinical results but on the battleground a business real deal between Bayer and Algeta.

This is a $800M transaction and Algeta received $61M upfront payment. Algeta is a Nordic public company and shares trading at many stock exchange markets. Less than 50 employees work for this company. Even the Eurozone encountered a string of economic drawbacks, Algeta was successful on latest fund raising and appealing Big partner (pharma).

by alveice Team (alveice@gmail.com)

2 comments:

  1. Beside of radioactive iodine labeled anti-CD20 antibody (Bexxar_I131), different nuclides (I111 and Y90) applied on the same antobody is under evaluation.

    Phase II Trial of Short-Course R-CHOP Followed by 90Y-Ibritumomab Tiuxetan in Previously Untreated High-Risk Elderly Diffuse Large B-Cell Lymphoma Patients. (Clin Cancer Res. 2010 Jun 11. )

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  2. Internal Yttrium-90 combined 5-Fu showed better response rate for liver metastasis

    Phase III Trial Comparing Protracted Intravenous Fluorouracil Infusion Alone or With Yttrium-90 Resin Microspheres Radioembolization for Liver-Limited Metastatic Colorectal Cancer Refractory to Standard Chemotherapy.

    J Clin Oncol. 2010 Jun 21.

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